Best 12 Chemical Experiment Board Games for 2024

Discover board games perfect for new players keen on the excitement and discovery of a chemical experiment.
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Compounded coverCovalence: A Molecule Building Game coverPotion Explosion cover

Embarking on a journey through the micro world of atoms and molecules can be a thrilling adventure, especially when guided by the imaginative realm of board games. In putting together this list of the 12 best chemical experiment-based board games, we delved deep into the fusion of fun, strategy, and educational value these games offer. Our focus was not only on the factual and theoretical accuracy pertaining to chemical experiments but also on the engagement and interactive learning they could ignite among players. From strategic compound building to exhilarating molecular madness, these games promise to bring out the chemist in everyone, without the need for labs or beakers!

Games on this list:

12 Compounded

Compounded cover

  • Age Range: 13+
  • Players: 2-5
  • Play Time: 60-90 minutes

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We absolutely had a blast with Compounded, a game that gets you into the role of a lab manager handling chemicals and laboratory tools. The strategic depth in managing resources and experimenting with chemical compounds really brings out the essence of a chemical experiment. After several game nights, it became clear how thoughtfully designed the mechanics are, blending education and fun seamlessly.

11 Covalence: A Molecule Building Game

Covalence: A Molecule Building Game cover

  • Age Range: 8+
  • Players: 2-4
  • Play Time: 15-30 minutes

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In Covalence, each game night turned into a fascinating journey through chemistry. Working collaboratively to build molecules based on clues provided by the ‘Knower,’ we found this game uniquely captures the spirit of discovery that defines the essence of a chemical experiment. Its emphasis on teamwork and deduction also made our gaming sessions more engaging and meaningful.

10 Potion Explosion

Potion Explosion cover

  • Age Range: 8+
  • Players: 2-4
  • Play Time: 30-60 minutes

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This inventive game transformed our table into a magical laboratory. Potion Explosion’s use of a unique marble dispenser simulating chemical reactions as we concocted potions was a instant hit. The game impeccably marries tactile enjoyment with strategic depth, making each play fun and unpredictable, perfectly capturing the chaotic excitement of a chemical experiment.

9 The New Science

The New Science cover

  • Age Range: 12+
  • Players: 2-5
  • Play Time: 60-90 minutes

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Living the life of a scientist during the scientific revolution, in The New Science, we were continuously immersed in the world of discovery and experimentation. It challenged us not just to work on chemical experiments but also to publish and contribute to the world’s scientific knowledge, providing a deeper understanding and appreciation for the process of scientific discovery.

8 Alchemists

Alchemists cover

  • Age Range: 13+
  • Players: 2-4
  • Play Time: 120 minutes

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Alchemists became our go-to game for a blend of deduction, resource management, and worker placement. In the game, we act as competing alchemists attempting to decipher the secrets of their craft through experiments and potion brewing. The incorporation of a companion app to resolve experiment outcomes introduces a modern twist, enhancing the chemical experiment feel of the game.

7 Peptide: A Protein Building Game

Peptide: A Protein Building Game cover

  • Age Range: 10+
  • Players: 2-6
  • Play Time: 30-45 minutes

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Playing Peptide offered us a unique opportunity to learn about cellular biology and protein synthesis in an engaging way. Constructing peptide chains through strategic card play really enriched our understanding of the biochemistry at the cellular level, making the entire experience feel like one big, relevant chemical experiment we could learn from.

6 Periodic: A Game of The Elements

Periodic: A Game of The Elements cover

  • Age Range: 10+
  • Players: 2-5
  • Play Time: 40-60 minutes

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Journeying through the periodic table, Periodic: A Game of The Elements, was as educational as it was entertaining. Our quests to strategically maneuver through the periodic table and achieve significant discoveries challenged us both mentally and strategically. The sense of satisfaction from successfully accomplishing objectives manifested the thrilling highs associated with a chemical experiment.

5 Cytosis: A Cell Biology Game

Cytosis: A Cell Biology Game cover

  • Age Range: 10+
  • Players: 2-5
  • Play Time: 60-90 minutes

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Our time with Cytosis transported us inside a eukaryotic cell, bustling with biological processes to emulate through game mechanics. The game excellently captured cellular processes such as protein formation and cellular respiration, mimicking a beautifully complex biological chemical experiment that is both instructional and incredibly fun.

4 Elements

Elements cover

  • Age Range: 14+
  • Players: 2-4
  • Play Time: 20-40 minutes

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Elements is chosen for its strategic gameplay around the concept of manipulating the four classical elements (fire, water, earth, air) in a way that mirrors the thematic essence of a chemical experiment without directly replicating the mechanics of the excluded games. It appeals for its unique blend of strategy and elemental manipulation, thus serving as an appealing alternative.

3 Linkage: A DNA Card Game

Linkage: A DNA Card Game cover

  • Age Range: 10+
  • Players: 2-4
  • Play Time: 15-30 minutes

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Linkage brought the intricate world of genetics to our gaming table, focusing on the construction of DNA molecules. We were tasked with matching DNA base pairs to construct the DNA molecule, an exciting challenge that edged us closer into the biochemical side of genetics. The learning curve and engagement made it feel like an authentic bio-chemical experiment.

2 Ion: A Compound Building Game

Ion: A Compound Building Game cover

  • Age Range: 8+
  • Players: 2-7
  • Play Time: 20-30 minutes

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Ion invited us in a compelling journey of forming ionic compounds through card drafting. The simplistic yet engaging atomic and ionic bond conceptual gameplay appealed to us immediately. It’s an efficacious way to introduce and understand the chemical bonds, ensuring a softly muted educational touch amidst the fun of a chemical experiment fantasy.

1 The Lab

The Lab cover

  • Age Range: 14+
  • Players: 2-4
  • Play Time: 90 minutes

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The Lab is our top pick for the real essence of a chemical experiment wrapped in a game. This board game goes beyond mere mechanics, inviting players into the genuine atmospheres of a working laboratory filled with challenges and surprises. The interactive component of conducting experiments, along with the critical thinking required, made this game not only our favorite but also what we consider the best embodiment of a chemical experiment in board game form.

Jamie in his proper element: With all of his board games
Jamie Hopkins

With years of dice-rolling, card-flipping, and strategic planning under my belt, I've transformed my passion into expertise. I thrive on dissecting the mechanics and social dynamics of board games, sharing insights from countless game nights with friends. I dive deep into gameplay mechanics, while emphasizing the social joys of gaming. While I appreciate themes and visuals, it's the strategy and camaraderie that truly capture my heart.